ascl4+ lewis structure

Achaete-scute family bHLH transcription factor 4 . Resources. Tng hp y v chi tit nht cn bng phng trnh iu ch t AsCl4 (Tetracloroasenat (III)) ra HCOOH (Axit formic) . Please help us improve further take a moment to fill our brief user survey. Antibody staining with HPA036116 in immunohistochemistry. Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. The dx2y2 level is at such a high level that it remains unoccupied in almost all d8 complexes. Specimen Requirements: Blood (two 4ml EDTA tubes, lavender top) or Extracted DNA (3ug in EB buffer) or Buccal Swab or Saliva (kits available upon request) Test Limitations: All sequencing technologies have limitations. Determine the correct point group for . As. There are no reviews for ASCL4 Antibody (NBP2-92741). Entry name i: ASCL4_HUMAN: Accession i: Q6XD76 Primary (citable) accession number: Q6XD76 Secondary accession number(s): Q7RTS2: Entry history i: Integrated into UniProtKB/Swiss-Prot: : February 5, 2008: Last sequence update: : July 5, 2004: Last modified: : May 25, 2022: This is version 133 of the entry and version 1 of the sequence. Ascl4. HPA036116. Basic helix-loop-helix transcription factors, such as ASCL4, are essential for the determination of cell fate and the development and differentiation of . 92 ASCL4, a basic helix-loop-helix transcription factor, is essential for the determination of cell fate and the development and differentiation of numerous tissues. The kit is designed based on the best knowledge of CRISPRa SAM technology. Validated Applications: IHC, IHC-P. Validated Species: Human. ASCL4 ( 1 gene ) Coverage: 99% at 20x. ASCL4 (Achaete-Scute Family BHLH Transcription Factor 4) is a Protein Coding gene. Emergency Roadside Assistance will come to you and assist you 24/7 for many roadside events like flat tire, out of gas, or towing. Diseases associated with ACSL4 include Intellectual Developmental Disorder, X-Linked 63 and Stroke, Ischemic . Expression. Although many cell products are maintained at 4C for years without loss of activity, shelf-life at 4C is highly variable. Among its related pathways are arachidonate biosynthesis III (6-desaturase, mammals) and Arachidonic acid metabolism . Although many cell products are maintained at 4C for years without loss of activity, shelf-life at 4C is highly variable. Target. (a) The electron configuration of Au is [Xe] 6s14f145d10. GSEA, gene set enrichment analysis. Function i GO - Molecular function i. DNA-binding transcription factor activity, RNA polymerase II-specific Source: GO . The efficiency of the activation can . Basic helix-loop-helix transcription factors, such as ASCL4, are essential for the determination of cell fate and the development and differentiation of numerous tissues (Jonsson et al., 2004 [PubMed 15475265]). Discovered in the 1970s, the tumor suppressor protein p53 (TP53) plays a critical role in the cellular response to various stresses, including DNA damage, hypoxia, nutrition starvation, and oncogene activation .Activation of p53 can lead to survival or death, depending on the levels of stress .Low levels of stress or damage trigger p53 activation to induce cell cycle arrest, DNA repair, and . Description. This analysis is performed by Next Generation Sequencing (NGS) and is designed to . Learn more I agree I agree Ascl4 em1(IMPC)J /Ascl4 em1(IMPC)J C57BL/6NJ-Ascl4 em1(IMPC)J /Mmjax: absent vibrissae: J:211773: Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO) Citing These Resources Choose from 1 of 3 ASCL4 antibodies, which have been validated in experiments with 6 images featured in our data gallery. . Phenotype data for mouse gene Ascl4. Quick Order. Overview; Perturbation Effects; Characterization; Description; Dependent Cell Lines . Color images are available online. For more info on ASCL4, check out the ASCL4 Infographic We have 30,000+ of these available, one for each gene! Diseases associated with ASCL4 include Secondary Hypertrophic Osteoarthropathy and Porokeratosis. Plasmid EF1a_ASCL4_P2A_Hygro_Barcode from Dr. Prashant Mali's lab contains the insert ASCL4 and is published in Cell Syst. Specimen Requirements: Blood (two 4ml EDTA tubes, lavender top) or Extracted DNA (3ug in EB buffer) or Buccal Swab or Saliva (kits available upon request) Test Limitations: All sequencing technologies have limitations. a) SbCI5 c) (Br3) e) IF5 g) BrF3 i) (H3Se)+ k) TeBr2C12 b) (Ascl4)- d) TeF2 f) (IBrCI) h) KrF2 ) (SnF6)2- ) CI2SO2 2. Cytogenetic location: 12q23.3 Genomic coordinates (GRCh38): 12:107,774,703-107,776,643 (from NCBI) TEXT. Plasmids containing this gene, or a homologous gene. Summary. shRNA sequences correspond to ASCL4 siRNA Gene Silencer sequences After transduction, stable cell lines expressing the shRNA may be isolated via selection with puromycin Biosafety - Lentiviral Particles are replication-incompetent and are designed to self-inactivate after transduction and integration of shRNA constructs into genomic DNA of . ASCL4-201 ENSP00000345420 ENST00000342331: Q6XD76 [Direct mapping] Achaete-scute homolog 4 . ASCL4 has 1,199 functional associations with biological entities spanning 8 categories (molecular profile, organism, functional term, phrase or reference, disease, phenotype or trait, chemical, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 38 datasets. Arsenic chloride is formed when Arsenic combines with three Chlorine atoms as Arsenic contains three valence electrons. We use cookies to ensure you get the best experience on our website. 03000 Transcription factors. 1 CRISPRa scramble vector, SKU GE100077. Expression of ASCL4 (bHLHa44, HASH4) in kidney tissue. HUGO Gene Nomenclature Committee (HGNC) approved gene symbol report : Entry status i: Reviewed (UniProtKB . Unreviewed-Annotation score: -Protein predicted i. Long-chain acyl-CoA synthetase-4 (ACSL4) has been hypothesized to modulate the metabolic fates of polyunsaturated FA (PUFA), including arachidonic acid (AA), but the in vivo actions of ACSL4 are unknown. Form. ASCL4 antibody LS-C749441 is an unconjugated rabbit polyclonal antibody to human ASCL4. By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount. Add 50 ul of distilled water. Ascl4. Gene Ontology (GO) annotations related to this gene include protein dimerization activity . In this infographic you will see the following information for ASCL4: database IDs, super-family, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post translational modifications, and related diseases . Predict the shape, state the hybridization of the central atom, and give the ideal bond angle (s) and any expected deviations for AsCl4 Shape: trigonal pyramidal O tetrahedral O seesaw T-shaped sp"d" hybrid AO where: m= and n = Ideal bond angle (s): (Select one or more.) Voxx CarLink ASCL4 owner's manual. Figure 1. For the second year you can renew the basic plan (without GPS) for $29.99, or with GPS for $79.99. Description achaete-scute family bHLH transcription factor 4 Also known as HASH4, bHLHa44 Species Homo sapiens Entrez ID 121549. H00916. . Receive our newsletter To keep up to date with the latest developments to our search engine, news from our market data analysis and improvements to our citation provision. Addgene Alerts Receive email alerts when new plasmids with this gene become available. Basic helix-loop-helix transcription factors, such as ASCL4, are essential for the determination of cell fate and the development and differentiation of . Hi Guys!Welcome back to Geometry of Molecules where we make chemistry more fun! Ferroptosis is a non-apoptotic form of programmed cell death and is related to various diseases. HGNC Approved Gene Symbol: ASCL4. ASCL4, a basic helix-loop-helix transcription factor, is essential for the determination of cell fate and the development and differentiation of numerous tissues. Description achaete-scute family bHLH transcription factor 4 Also known as HASH4, bHLHa44 Species Homo sapiens Entrez ID 121549. This plasmid is available through Addgene. ACSL4 (Acyl-CoA Synthetase Long Chain Family Member 4) is a Protein Coding gene. Curated assertions on the My Cancer Genome website are housed within a Knowledge Management System (KMS) created through a partnership with GenomOncology that serves as a warehouse of biomarker, disease, and drug ontologies; biomarker-driven cancer clinical trials; therapeutic, prognostic, and diagnostic assertions; and unstructured . Review with no image -- $10/7/6/$10 CAD/70 Yuan/1110 Yen; Review with an image -- $25/18/15/$25 CAD/150 Yuan/2500 Yen; Submit a Review. Discover Ascl4's significant phenotypes, expression, images, histopathology and more. Description. Identify and locate the symmetry elements in the species a) to l) whose Lewis structures and geometric structures you determined in problem 1. An important paralog of this gene is ASCL5. BackgroundIschemic stroke is the main cause of disability worldwide, leading to a serious socioeconomic burden. Invitrogen Anti-ASCL4 Polyclonal, Catalog # PA5-43650. Products. HUMAN ACHAETE-SCUTE HOMOLOG 4; HASH4. Ascl4 [d] Ascl4 [d] Expressed in. check them out. Validated for WB. Human ASCL4 (121549), Mouse Ascl4 (67341), Rat Ascl4 (299687), chicken ASCL4 (427912), dog ASCL4 (610742), cow ASCL4 (540730) Summary: Basic helix-loop-helix transcription factors, such as ASCL4, are essential for the determination of cell fate and the development and differentiation of numerous tissues (Jonsson et al., 2004 [PubMed 15475265. FIG. (b) The electron configuration of Au3+ is [Xe] 6s04f145d8. It is reactive with human and chimpanzee. Synonyms. ACSL4 (Acyl-CoA Synthetase Long Chain Family Member 4) is a Protein Coding gene. Tng hp phng trnh c [AsCl4] [AsF6] (Tetrachloroarsen hexafluoroarsenate) l cht tham gia. Arsenic Chloride. 2018 Nov 12. pii: S2405-4712(18)30433-2. doi: 10.1016/j.cels.2018.10.008. Objective. 5. Lyophilized powder. Registration enables users to use special features of this website, such as past The expression of Hash4 and Hash3 was analyzed by reverse transcriptase polymerase chain reaction (PCR . See complete history. Restrict the view to a region of the gene by dragging across the histogram to highlight the region of interest, or by using the sliders in the filters panel to the left. Schematic of data sources for My Cancer Genome. HUMAN ACHAETE-SCUTE HOMOLOG 4; HASH4. Human ASCL4. Acyl-CoA synthetase long-chain family member 4 (ACSL4) is one of Furthermore, ferroptosis accumulation and related protein expression (ASCL4, FTH1, and GPX4) were altered by LPS stimulation in HFD-challenged mice and suppressed by NADPH oxidase inhibition via Vas2870 in vivo . Schematic of data sources for My Cancer Genome. [d], [d], , [d], [d], [d] skin of abdomen [d] ASCL4 ( . Acyl-CoA synthetase long-chain family member 4 (ACSL4) is considered a target of ferroptosis, but its specific role in ischemic stroke remains unclear. ASCL4 ( 1 gene ) Coverage: 99% at 20x. The bHLH domain of the putative HASH4 protein shows most identity to HASH3/ASCL3. 12 ASCL4 Silencer Select Pre-designed, Validated, and Custom siRNA in Standard, HPLC, and In-vivo Ready Purities. Features (continued) Within the first year of service, you can upgrade to GPS from the included base service plan for $50.00. Go to complete Gene record for ASCL4; Go to Variation Viewer for ASCL4 variants; Summary. The protein encoded by this gene is an isozyme of the long-chain fatty-acid - coenzyme A ligase family. DNA replication was differentially enriched in the ASCL4 high expression phenotype. Safety. This antibody reacts with Human samples. Explain why AsCl4+ has a bond angle of 109.5 There are four bonding pairs around As (tetrahedral structure) and all the bonding pairs repel equally 9 Suggest why graphene is an excellent conductor of electricity Of particular interest, it was observed that mismatch repair was enriched in CELSR3 and ASCL4 (shown in Fig. Organism. Figure 1. Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Transcription factors Basic domains Mapped to neXtProt neXtProt - Evidence at protein level. Gene ID: 121549, updated on 25-Jan-2022. Tested in Western Blot (WB) applications. Moreover, ACSL4 was preferentially expressed in a panel of basal-like breast cancer cell lines and predicted their sensitivity to ferroptosis. Supplied as 100 L purified antibody (0.5 mg/mL). AuCl 4. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free . Unreviewed-Annotation score: -Protein predicted i. Chemical Engineering questions and answers. 09182 Protein families: genetic information processing. Gene Effect. ASCL4 (acyl-CoA synthetase 4) - Elevated expression associated with claudin-low and basal-like BC phenotypes; may boost arachidonic acid metabolism through PTGS2, ALOX5, and AKT/mTOR pathways In this study, we investigate . Answer to: What is the hybridization of AsCl4-? ASCL4 achaete-scute family bHLH transcription factor 4. [supplied by OMIM, Mar 2008] [supplied by OMIM, Mar 2008] A majority of malignant cells were weakly stained or negative. Diseases associated with ASCL4 include Secondary Hypertrophic Osteoarthropathy and Porokeratosis . Polyclonal. Rattus norvegicus (Rat) Status. It could be a transcriptional regulator involved in skin development.Basic helix-loop-helix transcription factors, such as ASCL4, are essential for the determination of cell fate and . We report the identification and cloning of a new, fourth member in the achaete-scute complex family of genes, Hash4 or Ascl4, which maps to chromosome 12q24.1. Pubmed ID Year Title Citations; 20351714: 2011: Poor replication of candidate genes for major depressive disorder using genome-wide association data. ASCL4. Congenital central hypoventilation syndrome. Cart . Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. Brite. Mechanistically, ACSL4 enriched cellular membranes with long polyunsaturated 6 fatty acids.